TBXA2R antibody (AA 51-150)

Catalog No. ABIN2690318

The Rabbit Polyclonal anti-TBXA2R antibody is suitable to detect TBXA2R in samples from Human. It has been validated for FACS, IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for TBXA2R antibody (AA 51-150) (ABIN2690318)

Target: TBXA2R (Thromboxane A2 Receptor (TBXA2R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBXA2R antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TBXA2R Antibody

Binding Specificity: AA 51-150

Purpose: TXA2R Polyclonal Antibody

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TXA2R

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TBXA2R

Target: TBXA2R (Thromboxane A2 Receptor (TBXA2R))

Alternative Name: TXA2R

Background:

Synonyms: TXA2-R, BDPLT13, Thromboxane A2 receptor, Prostanoid TP receptor, TBXA2R

Background: Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase.

Gene ID: 6915

UniProt: P21731