CD20 antibody

Catalog No. ABIN2704210

The Mouse Monoclonal anti-CD20 antibody has been validated for FACS. It is suitable to detect CD20 in samples from Human, Baboon, Rhesus Monkey and Cynomolgus.

Quick Overview for CD20 antibody (ABIN2704210)

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Reactivity: Human, Baboon, Rhesus Monkey, Cynomolgus

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD20 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: 2H7

Product Details anti-CD20 Antibody

Purpose: CD20 Unconjugated Antibody

Characteristics: The clone 2H7 recognizes the large extracellular loop of human CD20, mapped to the peptide sequence YNCEPANPSEKNSPST. CD20, a 33-36 kDa non-glycosylated type 1 transmembrane protein, is expressed by developing, resting and mature B cells, some follicular dendritic cells, and a small subset of mature T cells. B cell CD20 expression is lost upon differentiation into plasma cells. Functionally, CD20 activation contributes to B cell activation, proliferation, and differentiation

Purification: Purified

Purity: >95 %

Immunogen: Human tonsillar B cells

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD20

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Alternative Name: CD20

NCBI Accession: NM_152866

UniProt: P11836