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CD3 antibody

GMP Grade CD3 Reactivity: Human FACS Host: Mouse Monoclonal OKT3 unconjugated
Catalog No. ABIN2704232
$185.45
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  • Target See all CD3 Antibodies
    CD3
    Reactivity
    • 210
    • 93
    • 29
    • 20
    • 11
    • 11
    • 10
    • 8
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 241
    • 45
    • 20
    • 11
    • 6
    Mouse
    Clonality
    • 313
    • 6
    Monoclonal
    Conjugate
    • 106
    • 37
    • 29
    • 25
    • 19
    • 11
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD3 antibody is un-conjugated
    Application
    • 285
    • 96
    • 72
    • 66
    • 64
    • 39
    • 37
    • 26
    • 18
    • 17
    • 13
    • 9
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    Purified
    Purity
    > 95 %
    Grade
    GMP Grade
    Immunogen
    Human peripheral blood lymphocytes
    Clone
    OKT3
    Isotype
    IgG2a kappa
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS pH 7.2, 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Target
    CD3
    Alternative Name
    CD3 (CD3 Products)
    Synonyms
    CD3, AI504783, CD3epsilon, T3e, cd3-gamma, cd3g, cd3g-a, cd3g/d, cd3gd, t3g, CD3e molecule, CD3d molecule, CD3 antigen, epsilon polypeptide, CD3g molecule S homeolog, CD3E, CD3D, Cd3e, cd3g.S
    Background
    CD3ε is a 20kD peptide chain, which together with CD3λ, CD3δ, and CD3ζ, and a T cell receptor (α/β or γ/) form the CD3/T-cell receptor complex. It is a specific marker for T lymphocytes, NK T cells, and some thymocytes. Crosslinking of TCR initiates an intracellular signaling cascade resulting in cellular activation and proliferation. The OKT3 antibody shows potent immunosuppressive properties in vivo and has been proved effective in the treatment of renal, heart, and liver allograft rejection.
    NCBI Accession
    NM_000733
    UniProt
    P07766
    Pathways
    TCR Signaling, Ubiquitin Proteasome Pathway
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