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CD3 antibody

Name: CD3 antibody
SKU: ABIN2704232
Price: 185.45 USD
Availability: InStock

GMP Grade CD3 Reactivity: Human FACS Host: Mouse Monoclonal OKT3 unconjugated

FACS

Image no. 2 for anti-CD3 (CD3) antibody (ABIN2704232)

2 images

Catalog No. ABIN2704232

Datasheet as PDF

Target See all CD3 Antibodies

CD3
Reactivity
189

90

23

15

15

10

8

8

7

5

3

3

2

1
Human
Host
215

45

14

13

9
Mouse
Compatible Secondaries
Clonality
285

7
Monoclonal
Conjugate
88

33

29

23

22

11

7

7

6

5

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD3 antibody is un-conjugated
Application
267

81

55

44

43

40

28

23

9

9

8

7

4

3

2

2

2

2

2

2

2

1

1
Flow Cytometry (FACS)

Characteristics

CD3ε is a 20kD peptide chain, which together with CD3λ, CD3δ, and CD3ζ, and a T cell receptor (α/β or γ/) form the CD3/T-cell receptor complex. It is a specific marker for T lymphocytes, NK T cells, and some thymocytes. Crosslinking of TCR initiates an intracellular signaling cascade resulting in cellular activation and proliferation. The OKT3 antibody shows potent immunosuppressive properties in vivo and has been proved effective in the treatment of renal, heart, and liver allograft rejection.

Purification

Purified

Purity

>95 %

Grade

GMP Grade

Immunogen

Human peripheral blood lymphocytes

Clone

OKT3

Isotype

IgG2a kappa

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anti-CD3 (CD3) antibody (Biotin)
CD3 Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-57 Biotin

anti-CD3 (CD3) antibody (Biotin)
CD3 Reactivity: Human, Non-Human Primate FACS, IP, IHC (fro) Host: Mouse Monoclonal UCHT1 Biotin

anti-CD3 (CD3) antibody (APC)
CD3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal UCHT1 APC

anti-CD3 (CD3) antibody (PerCP)
CD3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal UCHT1 PerCP

anti-CD3 (CD3) antibody (PE)
CD3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal UCHT1 PE

Restrictions

For Research Use only
Format

Liquid

Concentration

0.5 mg/mL

Buffer

PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C
Target

CD3

Alternative Name

CD3 (CD3 Products)

Synonyms

CD3 antibody, AI504783 antibody, CD3epsilon antibody, T3e antibody, cd3-gamma antibody, cd3g antibody, cd3g-a antibody, cd3g/d antibody, cd3gd antibody, t3g antibody, CD3e molecule antibody, CD3d molecule antibody, CD3 antigen, epsilon polypeptide antibody, CD3g molecule S homeolog antibody, CD3E antibody, CD3D antibody, Cd3e antibody, cd3g.S antibody

Background

CD3ε is a 20kD peptide chain, which together with CD3λ, CD3δ, and CD3ζ, and a T cell receptor (α/β or γ/) form the CD3/T-cell receptor complex. It is a specific marker for T lymphocytes, NK T cells, and some thymocytes. Crosslinking of TCR initiates an intracellular signaling cascade resulting in cellular activation and proliferation. The OKT3 antibody shows potent immunosuppressive properties in vivo and has been proved effective in the treatment of renal, heart, and liver allograft rejection.

NCBI Accession

NM_000733

UniProt

P07766

Pathways

TCR Signaling, Ubiquitin Proteasome Pathway