CD38 antibody (FITC)
Quick Overview for CD38 antibody (FITC) (ABIN2704260)
Target
See all CD38 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Purpose
- CD38 FITC Antibody
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Characteristics
- The clone OKT10, a mouse monoclonal antibody, recognizes a 45 kDa, type II transmembrane cell surface glycoprotein known as CD38. The CD38 antigen is expressed on pre-B lymphocytes, plasma cells, thymocytes and monocytes. CD38 also presents on activated T lymphocytes, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. Antigen expression is detected during the early stage of T- and B-lymphocyte differentiation, then lost during the intermediate stage of maturation, only to reappear during the final stage of maturation. The CD38 antigen is expressed on 90 % of CD34+ cells and is not expressed on pluripotent stem cells. CD38 is expressed in T- and B-acute lymphoblastic leukemia (ALL), Burkitt's lymphoma, multiple myeloma, acute myeloid leukemia (AML), and chronic lymphocytic leukemia (CLL).
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Purification
- Purified
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Purity
- >95 %
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Immunogen
- Human acute lymphoblastic leukaemia cells
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Isotype
- IgG1, kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 200 μg/mL
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Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- 2-8°C, Conjugated antibodies should never be frozen.
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