BCAT1 antibody
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- Target See all BCAT1 Antibodies
- BCAT1 (Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1))
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Reactivity
- Human, Mouse, Dog
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This BCAT1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Homo sapiens branched chain amino-acid transaminase 1, cytosolic (BCAT1), transcript variant 1
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human BCAT1(NP_005495) produced in HEK293T cell.
- Clone
- 3F5
- Isotype
- IgG2a
- Top Product
- Discover our top product BCAT1 Primary Antibody
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- Application Notes
- WB 1:500~2000, IHC 1:150,
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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BCAT1 is a New MR Imaging-related Biomarker for Prognosis Prediction in IDH1-wildtype Glioblastoma Patients." in: Scientific reports, Vol. 7, Issue 1, pp. 17740, (2017) (PubMed).
: "Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia." in: Nature, Vol. 545, Issue 7655, pp. 500-504, (2017) (PubMed).
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BCAT1 is a New MR Imaging-related Biomarker for Prognosis Prediction in IDH1-wildtype Glioblastoma Patients." in: Scientific reports, Vol. 7, Issue 1, pp. 17740, (2017) (PubMed).
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- Target
- BCAT1 (Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1))
- Alternative Name
- BCAT1 (BCAT1 Products)
- Synonyms
- fj66g02 antibody, zgc:73157 antibody, wu:fj66g02 antibody, Bcatc antibody, BCATC antibody, BCT1 antibody, ECA39 antibody, MECA39 antibody, PNAS121 antibody, PP18 antibody, BCATc antibody, Eca39 antibody, branched chain amino-acid transaminase 1, cytosolic antibody, branched chain amino acid transaminase 1 antibody, branched chain amino-acid transaminase 1, cytosolic L homeolog antibody, branched chain aminotransferase 1, cytosolic antibody, bcat1 antibody, BCAT1 antibody, bcat1.L antibody, Bcat1 antibody
- Background
- This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.
- Molecular Weight
- 42.8 kDa
- Gene ID
- 586
- NCBI Accession
- NM_005504
- HGNC
- 586
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