Beclin 1 antibody

Catalog No. ABIN2716590

This Mouse Monoclonal antibody specifically detects Beclin 1 in WB, IHC, IF and FACS. It exhibits reactivity toward Human, Rat and Monkeyand has been mentioned in 1 publication.

Quick Overview for Beclin 1 antibody (ABIN2716590)

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Reactivity: Human, Rat, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Beclin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 3F3

Product Details anti-Beclin 1 Antibody

Characteristics: Homo sapiens beclin 1, autophagy related (BECN1)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human BECN1 (NP_003757) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-Beclin 1 antibody (ABIN2716590)

Deng, Pan, Cheng, Liu, Zhang, Zhang, Xu: "Regulation of SREBP-2 intracellular trafficking improves impaired autophagic flux and alleviates endoplasmic reticulum stress in NAFLD." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1862, Issue 3, pp. 337-350, (2017) (PubMed).

Target Details for Beclin 1

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Alternative Name: BECN1

Background: Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).

Molecular Weight: 51.7 kDa

Gene ID: 8678

NCBI Accession: NM_003766

HGNC: 8678

Pathways: Autophagy