Catalase antibody

Catalog No. ABIN2717108

Product Details anti-Catalase Antibody

Target: Catalase (CAT)

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Catalase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Characteristics: Homo sapiens catalase (CAT)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human CAT (NP_111743) produced in HEK293T cell.

Clone: 1B8

Isotype: IgG1

Application Details

Application Notes: WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Catalase

Target: Catalase (CAT)

Alternative Name: CAT (CAT Products)

Synonyms: 2210418N07 antibody, Cas-1 antibody, Cas1 antibody, Cs-1 antibody, CS1 antibody, Cat01 antibody, Catl antibody, fb68a12 antibody, wu:fb68a12 antibody, CAT antibody, CATA antibody, CG6871 antibody, CT21282 antibody, CatA antibody, DMCATHPO antibody, DROCATHPO antibody, Dmel\\CG6871 antibody, U00145 antibody, bs36h11.y1 antibody, cat antibody, GB11648 antibody, catalase antibody, Cat antibody, BA0843 antibody, DKFZp469E0232 antibody, catalase antibody, Catalase antibody, catalase, gene 2 antibody, CAT antibody, Cat antibody, cat antibody, cat.2 antibody, LOC769804 antibody, BA_0843 antibody

Background: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.

Molecular Weight: 59.6 kDa

Gene ID: 847

NCBI Accession: NM_001752

HGNC: 847

Pathways: Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism