PVRL1 antibody

Catalog No. ABIN2717251

Product Details anti-PVRL1 Antibody

Target: PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PVRL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Homo sapiens poliovirus receptor-related 1 (herpesvirus entry mediator C) (PVRL1), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human PVRL1(NP_002846) produced in HEK293T cell.

Clone: 6F8

Isotype: IgG1

Application Details

Application Notes: WB 1:2000, IHC 1:150, IF 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for PVRL1

Target: PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))

Alternative Name: PVRL1 (PVRL1 Products)

Synonyms: CD111 antibody, CLPED1 antibody, ED4 antibody, HIgR antibody, HVEC antibody, OFC7 antibody, PRR antibody, PRR1 antibody, PVRR antibody, PVRR1 antibody, SK-12 antibody, nectin-1 antibody, prr1 antibody, PVRL1 antibody, pvrl1 antibody, AI835281 antibody, AW549174 antibody, Cd111 antibody, HveC antibody, cd111 antibody, cd112 antibody, clped1 antibody, ed4 antibody, higr antibody, hveb antibody, hvec antibody, nectin-2 antibody, ofc7 antibody, prr antibody, prr2 antibody, pvrl2 antibody, pvrl2.L antibody, pvrr antibody, pvrr1 antibody, pvrr2 antibody, sk-12 antibody, nectin cell adhesion molecule 1 antibody, nectin-1 antibody, Poliovirus receptor-related protein 1 antibody, poliovirus receptor-related 1 (herpesvirus entry mediator C) antibody, nectin cell adhesion molecule 2 L homeolog antibody, NECTIN1 antibody, LOC100145553 antibody, pvrl1 antibody, nectin1 antibody, Nectin1 antibody, PVRL1 antibody, nectin2.L antibody

Background: This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

Molecular Weight: 54 kDa

Gene ID: 5818

NCBI Accession: NM_002855

HGNC: 5818

Pathways: Cell-Cell Junction Organization