SNCG antibody

Catalog No. ABIN271916

The Rabbit Polyclonal anti-SNCG antibody is suitable to detect SNCG in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for SNCG antibody (ABIN271916)

Target: SNCG (Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNCG antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SNCG Antibody

Specificity: This antibody detects endogenous levels of Synuclein γ protein. (region surrounding Ala111)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Purity: > 95 % pure by SDS-PAGE

Application Details

Application Notes: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: DO NOT FREEZE!

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for SNCG

Target: SNCG (Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG))

Alternative Name: gamma-Synuclein / SNCG

Background: The synucleins, including alpha-synuclein (also designated NACP for nonamyloid component precursor), beta-synuclein (also designated PNP 14 for phosphoneuroprotein 14), and gamma-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1) are presynaptic proteins abundant in neurons. alpha-Synuclein, identified as a component of Alzheimers disease amyloid plaques, is localized to neuronal cell bodies and synapses. Coordinate expression of alpha-synuclein and beta-synuclein may be important during hematopoetic cell differentiation. A mutant form of alpha-synuclein is found in patients with early onset Parkinsons disease. gamma-Synuclein is associated with axonal pathology in Parkinsons disease.Synonyms: BCSG1, Breast cancer-specific gene 1 protein, PERSYN, PRSN, Synoretin, Synuclein gamma

Molecular Weight: approx. 20 kDa

Gene ID: 6623

NCBI Accession: NP_003078

UniProt: O76070