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NUB1 antibody

NUB1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN271950
  • Target See all NUB1 Antibodies
    NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
    Reactivity
    • 35
    • 13
    • 3
    • 2
    • 1
    Human, Mouse
    Host
    • 31
    • 3
    • 1
    Rabbit
    Clonality
    • 33
    • 2
    Polyclonal
    Conjugate
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NUB1 antibody is un-conjugated
    Application
    • 28
    • 20
    • 18
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody detects endogenous levels of NUB1 protein. (region surrounding Tyr601)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Mouse.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    Purity
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product NUB1 Primary Antibody
  • Application Notes
    ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    DO NOT FREEZE!
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
    Alternative Name
    NUB1 (NUB1 Products)
    Background
    NUB1 is a ubiquitin-like protein that controls vital biological events through its conjugation to cullin proteins. NUB1 is a negative regulator of the NEDD8 system that recruits NEDD8 and its conjugates to the proteasome for degradation. It is, therefore a cell growth regulator. The UBA domain of NUB1 is the specific acceptor for the linear ubiquitin precursor. NUB1 is composed of 601 amino acids. It is an interferon-inducible protein and predominantly localizes in the nucleus. NUB1 is specifically expressed in adult human testis, ovary, heart, and skeletal muscle tissues.Synonyms: NEDD8 μLtimate buster 1, NYREN18, Negative regulator of ubiquitin-like proteins 1, Renal carcinoma antigen NY-REN-18
    Molecular Weight
    approx. 70 kDa
    Gene ID
    51667
    NCBI Accession
    NP_057202
    UniProt
    Q9Y5A7
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