ERCC4 antibody

Catalog No. ABIN2720430

Product Details anti-ERCC4 Antibody

Target: ERCC4 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4))

Reactivity: Human, Mouse, Rat, Dog, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This ERCC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Characteristics: Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 4 (ERCC4)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human ERCC4(NP_005227) produced in HEK293 cell.

Clone: 3H10

Isotype: IgG1

Application Details

Application Notes: WB 1:200~500, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ERCC4

Target: ERCC4 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4))

Alternative Name: ERCC4 (ERCC4 Products)

Synonyms: ERCC11 antibody, FANCQ antibody, RAD1 antibody, XPF antibody, AI606920 antibody, Xpf antibody, RGD1560340 antibody, fi03a05 antibody, zgc:63468 antibody, wu:fi03a05 antibody, ercc11 antibody, rad1 antibody, xpf antibody, ERCC4 antibody, LOC100231158 antibody, ERCC excision repair 4, endonuclease catalytic subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 4 antibody, excision repair cross-complementation group 4 antibody, excision repair cross-complementation group 4 L homeolog antibody, ERCC4 antibody, Ercc4 antibody, ercc4 antibody, ercc4.L antibody, XPF antibody

Background: The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).

Molecular Weight: 104.3 kDa

Gene ID: 2072

NCBI Accession: NM_005236

HGNC: 2072

Pathways: DNA Damage Repair