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PKD2 antibody

PKD2 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN272069
  • Target See all PKD2 Antibodies
    PKD2 (Protein Kinase D2 (PKD2))
    Reactivity
    • 48
    • 18
    • 8
    • 3
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 44
    • 4
    • 1
    Rabbit
    Clonality
    • 38
    • 11
    Polyclonal
    Conjugate
    • 27
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PKD2 antibody is un-conjugated
    Application
    • 36
    • 31
    • 27
    • 7
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects endogenous levels of PKD2 protein. (region surrounding Ala872)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product PKD2 Primary Antibody
  • Application Notes
    ELISA: 1/5000approx. 1/10000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PKD2 (Protein Kinase D2 (PKD2))
    Alternative Name
    PRKD2 / PKD2 (PKD2 Products)
    Background
    The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.Synonyms: HSPC187, PKC-D2, Serine/threonine-protein kinase D2, nPKC-D2
    Molecular Weight
    approx. 96 kDa
    Gene ID
    25865
    NCBI Accession
    NP_001073349
    UniProt
    Q9BZL6
    Pathways
    cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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