Gephyrin antibody

Catalog No. ABIN2721815

The Mouse Monoclonal anti-Gephyrin antibody (Clone 5B6) (ABIN2721815) specifically detects Gephyrin in WB, FACS and IF. The antibody is reactive with Human samples.

Quick Overview for Gephyrin antibody (ABIN2721815)

Target: Gephyrin (GPHN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Gephyrin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 5B6

Product Details anti-Gephyrin Antibody

Characteristics: Homo sapiens gephyrin (GPHN), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human GPHN(NP_065857)

Isotype: IgG2a

Application Details

Application Notes: WB 1:2000, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Gephyrin

Target: Gephyrin (GPHN)

Alternative Name: GPHN

Background: This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.

Molecular Weight: 83.3 kDa

Gene ID: 10243

NCBI Accession: NM_020806

HGNC: 10243

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development