T-Box 22 antibody

Catalog No. ABIN272263

This Rabbit Polyclonal antibody specifically detects T-Box 22 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for T-Box 22 antibody (ABIN272263)

Target: T-Box 22 (TBX22)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 22 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-T-Box 22 Antibody

Specificity: This antibody detects endogenous levels of TBX22 protein. (region surrounding Ala30)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Purity: > 95 % pure by SDS-PAGE

Application Details

Application Notes: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: DO NOT FREEZE!

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for T-Box 22

Target: T-Box 22 (TBX22)

Alternative Name: TBX22

Background: The T-box (TBX) motif is present in a family of genes whose structural features and expression patterns support their involvement in developmental gene regulation. The TBX gene family are largely conserved throughout metazoan evolution, and these genes code for putative transcription factors that share a uniquely defining DNA-binding domain. TBX genes are a family of developmental regulators with more than 20 members recently identified in invertebrates and vertebrates. Mutations in TBX genes are associated with the onset of several human diseases. Our understanding of functional mechanisms of TBX products has come mainly from the prototypical T/Brachyury, which is a transcription activator. The TBX genes constitute a family of transcriptional regulatory genes that are implicated in a variety of developmental processes ranging from the formation of germ layers to the organizational patterning of the central nervous system.Synonyms: T-box protein 22, T-box transcription factor TBX22, TBOX22

Molecular Weight: approx. 60 kDa

Gene ID: 50945

NCBI Accession: NP_001103348

UniProt: Q9Y458