T-Box 22 antibody (Middle Region)

Catalog No. ABIN2777562

This Rabbit Polyclonal antibody specifically detects T-Box 22 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Pig and Rabbit.It has been mentioned in 1 publication

Quick Overview for T-Box 22 antibody (Middle Region) (ABIN2777562)

Target: T-Box 22 (TBX22)

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 22 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-T-Box 22 Antibody

Binding Specificity: Middle Region

Purpose: TBX22 Antibody - middle region

Sequence: QSMHKYKPRV HVIEQGSSVD LSQIQSLPTE GVKTFSFKET EFTTVTAYQN

Predicted Reactivity: Cow: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against TBX22. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBX22

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32745-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-T-Box 22 antibody (ABIN2777562)

Suphapeetiporn, Tongkobpetch, Siriwan, Shotelersuk: "TBX22 mutations are a frequent cause of non-syndromic cleft palate in the Thai population." in: Clinical genetics, Vol. 72, Issue 5, pp. 478-83, (2007) (PubMed).

Target Details for T-Box 22

Target: T-Box 22 (TBX22)

Alternative Name: TBX22

Background:

Background Information: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: T-box 22

Alternative Symbols: CPX, CLPA, TBXX, ABERS, dJ795G23.1

Protein Name: T-box transcription factor TBX22

Molecular Weight: 58kDa

Gene ID: 50945

NCBI Accession: NP_058650

UniProt: Q9Y458