ADRA1B antibody

Catalog No. ABIN272288

The Rabbit Polyclonal anti-ADRA1B antibody is suitable to detect ADRA1B in samples from Human, Mouse and Rat. It has been validated for WB, IHC (p) and IF.

Quick Overview for ADRA1B antibody (ABIN272288)

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRA1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-ADRA1B Antibody

Specificity: This antibody detects endogenous levels of AR-β1 protein. (region surrounding Ala302)

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Purity: > 95 % pure by SDS-PAGE

Application Details

Application Notes: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: DO NOT FREEZE!

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for ADRA1B

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Alternative Name: alpha-1B Adrenergic Receptor

Background: Alpha-1B adrenergic receptors couple to Gq/11 and induce neoplastic transformation in NIH-3T3 cell transfectants. Alpha-1B receptors (a1B-AR) can form hetero-oligomers with alpha-1A and alpha-1D receptors. α1B-AR transcripts are abundant in heart, brain and kidney.Synonyms: ADRA1B, Alpha 1B-adrenoceptor, Alpha 1B-adrenoreceptor

Molecular Weight: approx. 51 kDa

Gene ID: 147

NCBI Accession: NP_000670

UniProt: P35368

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process