Cadherin-16 antibody

Catalog No. ABIN272295

The Rabbit Polyclonal anti-Cadherin-16 antibody (ABIN272295) specifically detects Cadherin-16 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for Cadherin-16 antibody (ABIN272295)

Target: Cadherin-16 (CDH16)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin-16 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Cadherin-16 Antibody

Specificity: This antibody detects endogenous levels of Cadherin-16 protein. (region surrounding Met810)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Purity: > 95 % pure by SDS-PAGE

Application Details

Application Notes: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: DO NOT FREEZE!

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for Cadherin-16

Target: Cadherin-16 (CDH16)

Alternative Name: Cadherin-16

Background: The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-16, also known as Ksp-Cadherin, is a type I membrane protein which is kidney-specific. Cadherin-16 is expressed exclusively in the basolateral membrane of renal tubular epithelial cells. The human Ksp-cadherin gene (Cadherin-16) maps to chromosome 16q21-proximal 16q22. The mouse Ksp-cadherin gene was localized to a highly syntenic region of distal Chromosome 8.Synonyms: CDH16, KSP-Cadherin, Kidney-specific cadherin

Molecular Weight: approx. 90 kDa

Gene ID: 1014

NCBI Accession: NP_001191673

UniProt: O75309