ITM2B antibody

Catalog No. ABIN2723906

This Mouse Monoclonal antibody specifically detects ITM2B in WB, IHC and FACS. It exhibits reactivity toward Human.

Quick Overview for ITM2B antibody (ABIN2723906)

Target: ITM2B (Integral Membrane Protein 2B (ITM2B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITM2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 1C11

Product Details anti-ITM2B Antibody

Characteristics: Homo sapiens integral membrane protein 2B (ITM2B)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human ITM2B (NP_068839) produced in HEK293T cell.

Isotype: IgG2a

Application Details

Application Notes: WB 1:2000, IHC 1:150, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ITM2B

Target: ITM2B (Integral Membrane Protein 2B (ITM2B))

Alternative Name: ITM2B

Background: Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.

Molecular Weight: 30.2 kDa

Gene ID: 9445

NCBI Accession: NM_021999

HGNC: 9445