LEMD3 antibody

Catalog No. ABIN2724627

The Mouse Monoclonal anti-LEMD3 antibody (Clone 3C8) (ABIN2724627) specifically detects LEMD3 in WB and FACS. The antibody is reactive with Human and Monkey samples.

Quick Overview for LEMD3 antibody (ABIN2724627)

Target: LEMD3 (LEM Domain Containing 3 (LEMD3))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This LEMD3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 3C8

Product Details anti-LEMD3 Antibody

Characteristics: Homo sapiens LEM domain containing 3 (LEMD3), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human LEMD3 (NP_055134) produced in HEK293T cell.

Isotype: IgG2b

Application Details

Application Notes: WB 1:500~2000, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for LEMD3

Target: LEMD3 (LEM Domain Containing 3 (LEMD3))

Alternative Name: LEMD3

Background: This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.

Molecular Weight: 99.8 kDa

Gene ID: 23592

NCBI Accession: NM_014319

HGNC: 23592