LMAN1 antibody

Catalog No. ABIN2724841

The Mouse Monoclonal anti-LMAN1 antibody has been validated for WB, IHC, IF and FACS. It is suitable to detect LMAN1 in samples from Human, Rat, Dog and Monkey.

Quick Overview for LMAN1 antibody (ABIN2724841)

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Reactivity: Human, Rat, Dog, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This LMAN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 1A8

Product Details anti-LMAN1 Antibody

Characteristics: Homo sapiens lectin, mannose-binding, 1 (LMAN1)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human LMAN1 (NP_005561) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:200~500, IHC 1:150, IF 1:100, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for LMAN1

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Alternative Name: LMAN1

Background: The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

Molecular Weight: 54.2 kDa

Gene ID: 3998

NCBI Accession: NM_005570

HGNC: 3998