LMAN1 antibody
Quick Overview for LMAN1 antibody (ABIN2724842)
Target
See all LMAN1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Characteristics
- Homo sapiens lectin, mannose-binding, 1 (LMAN1)
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Purification
- Purified from mouse ascites fluids by affinity chromatography
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Immunogen
- Full length human recombinant protein of human LMAN1 (NP_005561) produced in HEK293T cell.
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Isotype
- IgG1
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Application Notes
- WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
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Comment
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The concentration of the product may vary between diferrent lots.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5-1.0 mg/mL
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Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))
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Alternative Name
- LMAN1
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Background
- The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
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Molecular Weight
- 54.2 kDa
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Gene ID
- 3998
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NCBI Accession
- NM_005570
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HGNC
- 3998
Target
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