MMACHC antibody

Catalog No. ABIN2726123

This Mouse Monoclonal antibody specifically detects MMACHC in WB and FACS. It exhibits reactivity toward Human.

Quick Overview for MMACHC antibody (ABIN2726123)

Target: MMACHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MMACHC antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 4E9

Product Details anti-MMACHC Antibody

Characteristics: Homo sapiens methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria (MMACHC)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human MMACHC(NP_056321) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:2000, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for MMACHC

Target: MMACHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC))

Alternative Name: MMACHC

Background: The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.

Gene ID: 25974

NCBI Accession: NM_015506

HGNC: 25974