GDF15 antibody
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- Target See all GDF15 Antibodies
- GDF15 (Growth Differentiation Factor 15 (GDF15))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This GDF15 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
- Characteristics
- Homo sapiens peptide deformylase (mitochondrial) (PDF), nuclear gene encoding mitochondrial protein
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human PDF (NP_071736) produced in HEK293T cell.
- Clone
- 3C12
- Isotype
- IgG1
- Top Product
- Discover our top product GDF15 Primary Antibody
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anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody
Verified GDF15 Reactivity: Human WB, ELISA, IHC, FACS Host: Goat Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79) antibodyGDF15 Reactivity: Human WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 30-308) antibodyGDF15 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 221-308) antibodyGDF15 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79), (N-Term) antibodyGDF15 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB30209 unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody (Biotin)GDF15 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal Biotin
anti-Growth Differentiation Factor 15 (GDF15) (AA 195-308) antibodyGDF15 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 198-308) antibodyGDF15 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 16-143) antibodyGDF15 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (N-Term) antibodyGDF15 Reactivity: Human WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500, IF 1:100, FLOW 1:100
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- GDF15 (Growth Differentiation Factor 15 (GDF15))
- Alternative Name
- PDF (GDF15 Products)
- Background
- Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells.
- Molecular Weight
- 19.4 kDa
- Gene ID
- 64146
- NCBI Accession
- NM_022341
- HGNC
- 64146
- Pathways
- SARS-CoV-2 Protein Interactome
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