PGAM2 antibody

Catalog No. ABIN2728771

The Mouse Monoclonal anti-PGAM2 antibody is suitable to detect PGAM2 in samples from Human. It has been validated for WB, IHC and IF.

Quick Overview for PGAM2 antibody (ABIN2728771)

Target: PGAM2 (phosphoglycerate Mutase 2 (Muscle) (PGAM2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PGAM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 1C11

Product Details anti-PGAM2 Antibody

Characteristics: Homo sapiens phosphoglycerate mutase 2 (muscle) (PGAM2)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human PGAM2(NP_000281) produced in HEK293T cell.

Isotype: IgG2b

Application Details

Application Notes: WB 1:2000, IHC 1:150, IF 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for PGAM2

Target: PGAM2 (phosphoglycerate Mutase 2 (Muscle) (PGAM2))

Alternative Name: PGAM2

Background: Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X.

Molecular Weight: 28.6 kDa

Gene ID: 5224

NCBI Accession: NM_000290

HGNC: 5224