POLR2J2 antibody

Catalog No. ABIN2729322

This Mouse Monoclonal antibody specifically detects POLR2J2 in WB, FACS, IF and IHC. It exhibits reactivity toward Human.

Quick Overview for POLR2J2 antibody (ABIN2729322)

Target: POLR2J2 (Polymerase (RNA) II (DNA Directed) Polypeptide J2 (POLR2J2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This POLR2J2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)

Clone: 3G4

Product Details anti-POLR2J2 Antibody

Characteristics: Homo sapiens polymerase (RNA) II (DNA directed) polypeptide J2 (POLR2J2)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human POLR2J2 (NP_116581) produced in HEK293T cell.

Isotype: IgG2a

Application Details

Application Notes: WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for POLR2J2

Target: POLR2J2 (Polymerase (RNA) II (DNA Directed) Polypeptide J2 (POLR2J2))

Alternative Name: POLR2J2

Background: This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo.

Molecular Weight: 12.9 kDa

Gene ID: 246721

NCBI Accession: NM_032959

HGNC: 246721