SOX17 antibody (AA 177-414)

Catalog No. ABIN2732433

There are 4+ publications for this product available. The Mouse Monoclonal anti-SOX17 antibody is suitable to detect SOX17 in samples from Human. It has been validated for WB, IHC, IF and FACS.

Quick Overview for SOX17 antibody (AA 177-414) (ABIN2732433)

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SOX17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 3B10

Product Details anti-SOX17 Antibody

Binding Specificity: AA 177-414

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Human recombinant protein fragment corresponding to amino acids 177-414 of human SOX17 (NP_071899) produced in E.coli.

Isotype: IgG1

Application Details

Application Notes: WB 1:5000, IHC 1:50, IF 1:50~100, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS ( pH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-SOX17 antibody (ABIN2732433)

Imamura, Fujita, Tagawa, Ikura, Chen, Homma, Tamura, Mao, Taniguchi, Motoki, Nakabayashi, Ito, Yamada, Tomii, Okano, Kaye, Finkbeiner, Okazawa: "Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries." in: Scientific reports, Vol. 6, pp. 33861, (2016) (PubMed).

Takeuchi, Nakatsuji, Suemori: "Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture." in: Scientific reports, Vol. 4, pp. 4488, (2014) (PubMed).

Pennarossa, Maffei, Campagnol, Tarantini, Gandolfi, Brevini: "Brief demethylation step allows the conversion of adult human skin fibroblasts into insulin-secreting cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 22, pp. 8948-53, (2013) (PubMed).

Zhang, Cruz, Terry, Remotti, Matushansky: "Terminal differentiation and loss of tumorigenicity of human cancers via pluripotency-based reprogramming." in: Oncogene, Vol. 32, Issue 18, pp. 2249-60, 2260.e1-21, (2013) (PubMed).

Target Details for SOX17

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Alternative Name: SOX17

Molecular Weight: 43.9 kDa

Gene ID: 64321

NCBI Accession: NM_022454

HGNC: 64321