FDFT1 antibody

Catalog No. ABIN2732645

This Mouse Monoclonal antibody specifically detects FDFT1 in WB, IHC, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for FDFT1 antibody (ABIN2732645)

Target: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FDFT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 1H9

Product Details anti-FDFT1 Antibody

Characteristics: Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human FDFT1(NP_004453) produced in HEK293T cell.

Isotype: IgG2b

Application Details

Application Notes: WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for FDFT1

Target: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Alternative Name: FDFT1

Background: This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.

Molecular Weight: 47.9 kDa

Gene ID: 2222

NCBI Accession: NM_004462

HGNC: 2222

Pathways: Regulation of Lipid Metabolism by PPARalpha