TGFA antibody (AA 34-43)

Catalog No. ABIN2744784

The Mouse Monoclonal anti-TGFA antibody (Clone 1E8-G6) (ABIN2744784) specifically detects TGFA in IHC, IF, FACS, ELISA and IHC (p). The antibody is reactive with Human, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for TGFA antibody (AA 34-43) (ABIN2744784)

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Reactivity: Human, Rabbit, Zebrafish (Danio rerio)

Host: Mouse

Clonality: Monoclonal

Conjugate: This TGFA antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1E8-G6

Product Details anti-TGFA Antibody

Binding Specificity: AA 34-43

Specificity: Human TGFA / TGF Alpha

Purification: Protein G purified

Immunogen: A 10-amino acid synthetic peptide (aa34-43) from human TGF alpha.

Type of Immunogen: Synthetic peptide

Isotype: IgM kappa

Application Details

Application Notes: Approved: ELISA, Flo (0.5 - 1 μg/10 x10⁶), IF (1 - 2 μg/mL), IHC, IHC-P (1 - 2 μg/mL)

Usage: TGF alpha is a growth factor with 33 % homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype. This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. Staining with the antibody is completely blocked by the peptide used for raising this antibody. ELISA: Order BSA-free format for coating.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C to 8°C.

Target Details for TGFA

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Alternative Name: TGFA / TGF alpha

Background: Name/Gene ID: TGFA
Family: TGF beta

Synonyms: TGFA, Etgf, TFGA, TGF Alpha, Tgf type 1, TGF-alpha, Egf-like tgf

Gene ID: 7039

Pathways: NF-kappaB Signaling, RTK Signaling, EGFR Signaling Pathway