Uroplakin 3A antibody (AA 260-279)

Catalog No. ABIN2745217

This Rabbit Polyclonal antibody specifically detects Uroplakin 3A in WB, IP, IF and FACS. It exhibits reactivity toward Human and Orang-Utan.

Quick Overview for Uroplakin 3A antibody (AA 260-279) (ABIN2745217)

Target: Uroplakin 3A (UPK3A)

Reactivity: Human, Orang-Utan

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uroplakin 3A antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-Uroplakin 3A Antibody

Binding Specificity: AA 260-279

Specificity: Human UPK3A / UPK3 / Uroplakin III

Purification: Protein A purified

Immunogen: A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human Uroplakin 3A. Percent identity by BLAST analysis: Human, Orangutan (100%), Gorilla (95%), Monkey, Marmoset, Ferret, Pig (90%), Mouse, Rabbit, Dog (85%), Horse (80%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: Flo (0.5 - 1 μg/10 x10⁶), IF (1 - 2 μg/mL), IP, WB (0.5 - 1 μg/mL)

Usage: Uroplakin 3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. Uroplakin 3A may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. Uroplakin 3A has been shown as a helpful marker for the detection of bladder cancer.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C to 8°C.

Target Details for Uroplakin 3A

Target: Uroplakin 3A (UPK3A)

Alternative Name: UPK3A / UPK3 / Uroplakin III

Background: Name/Gene ID: UPK3A

Synonyms: UPK3A, Uroplakin 3, Uroplakin 3A, Uroplakin III, UPIII, UP3A, UPIIIA, UPK3, Uroplakin-3a

Gene ID: 7380