VWF antibody (AA 845-949)

Catalog No. ABIN2745310

This Mouse Monoclonal antibody specifically detects VWF in WB, IHC, IP, FACS, IF, ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for VWF antibody (AA 845-949) (ABIN2745310)

Target: VWF (Von Willebrand Factor (VWF))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This VWF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3E2D10

Product Details anti-VWF Antibody

Binding Specificity: AA 845-949

Specificity: Human VWF / Von Willebrand Factor

Purification: Protein G purified

Immunogen: Amino acids 845-949 were used as the immunogen for this vWF antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: ELISA, Flo (0.5 - 1 μg/10 x10⁶), IF (0.5 - 1 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)

Usage: von Willebrand Factor is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This vWF antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen. ELISA: Order BSA-free antibody format for coating.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C to 8°C.

Target Details for VWF

Target: VWF (Von Willebrand Factor (VWF))

Alternative Name: VWF / Von Willebrand Factor

Background: Name/Gene ID: VWF

Synonyms: VWF, Coagulation factor VIII VWF, F8VWF, VWD, Von Willebrand factor

Gene ID: 7450