Fission 1 antibody

Catalog No. ABIN2745530

This Rabbit Polyclonal antibody specifically detects Fission 1 in WB, ICC and IP. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Fission 1 antibody (ABIN2745530)

Target: Fission 1 (FIS1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fission 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Product Details anti-Fission 1 Antibody

Purpose: anti-Fis1, pAb

Specificity: Recognizes human, mouse and rat Fis1.

Characteristics: Polyclonal Antibody. Recognizes human, mouse and rat Fis1. Source: Rabbit. Applications: ICC, IP, WB. Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide. Fis1 promotes the fragmentation of the mitochondrial network and its perinuclear clustering. It can induce cytochrome c release from mitochondria to the cytosol, ultimately leading to apoptosis. It also mediates peroxisomal fission.

Immunogen: Recombinant human Fis1.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for Fission 1

Target: Fission 1 (FIS1)

Alternative Name: Fis1

Background:

Alternate Names/Synonyms: Mitochondrial Fission 1 Protein, Tetratricopeptide Repeat Protein 11, TTC 11

Product Description: Fis1 promotes the fragmentation of the mitochondrial network and its perinuclear clustering. It can induce cytochrome c release from mitochondria to the cytosol, ultimately leading to apoptosis. It also mediates peroxisomal fission.

UniProt: Q9Y3D6

Pathways: Positive Regulation of Endopeptidase Activity