LYVE1 antibody (AA 24-232)

Catalog No. ABIN2745542

This Rabbit Polyclonal antibody specifically detects LYVE1 in WB, IHC and FACS. It exhibits reactivity toward Human.

Quick Overview for LYVE1 antibody (AA 24-232) (ABIN2745542)

Target: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LYVE1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-LYVE1 Antibody

Binding Specificity: AA 24-232

Purpose: anti-LYVE-1 (human), pAb

Specificity: Recognizes human LYVE-1.

Characteristics: Polyclonal Antibody. Recognizes human LYVE-1. Source: Rabbit. Applications: FACS, IHC, WB. Lyophilized. LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. Like CD44, the LYVE-1 Molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 Molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.

Purification: Protein A purified.

Immunogen: Recombinant human LYVE-1 (aa24-232).

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: Lyophilized.

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Expiry Date: 6 months

Target Details for LYVE1

Target: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Alternative Name: Lyve1

Background:

Alternate Names/Synonyms: Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1, CRSBP-1

Product Description: LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. Like CD44, the LYVE-1 Molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 Molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.

UniProt: Q9Y5Y7

Pathways: Glycosaminoglycan Metabolic Process