Natriuretic Peptide Receptor B / PGCB (C-Term) antibody

Catalog No. ABIN2746994

This Rabbit Polyclonal antibody specifically detects Natriuretic Peptide Receptor B / PGCB in WB, CM, ICC, IF, IP, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat. It has been mentioned in 7+ publications

Quick Overview for Natriuretic Peptide Receptor B / PGCB (C-Term) antibody (ABIN2746994)

Target: Natriuretic Peptide Receptor B / PGCB

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Confocal Microscopy (CM), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA

Product Details

Binding Specificity: C-Term

Purification: Affinity Purified

Immunogen: Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase B protein.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.75-1.20 μg/μL

References

Thong, Müller, Feuerstacke, Mietens, Stammler, Middendorff: "Neutral endopeptidase (CD10) is abundantly expressed in the epididymis and localized to a distinct population of epithelial cells--its relevance for CNP degradation." in: Molecular and cellular endocrinology, Vol. 382, Issue 1, pp. 234-43, (2014) (PubMed).

Müller, Mukhopadhyay, Davidoff, Middendorff: "Cyclic GMP signaling in rat urinary bladder, prostate, and epididymis: tissue-specific changes with aging and in response to Leydig cell depletion." in: Reproduction (Cambridge, England), Vol. 142, Issue 2, pp. 333-43, (2011) (PubMed).

Müller, Hida, Guidone, Speth, Michurina, Enikolopov, Middendorff: "Expression of guanylyl cyclase (GC)-A and GC-B during brain development: evidence for a role of GC-B in perinatal neurogenesis." in: Endocrinology, Vol. 150, Issue 12, pp. 5520-9, (2010) (PubMed).

Müller, Hildebrand, Lübberstedt, Kuhn, Middendorff: "The membrane receptors guanylyl cyclase-A and -B undergo distinctive changes in post-translational modification during brain development." in: Journal of neurochemistry, Vol. 115, Issue 4, pp. 1024-34, (2010) (PubMed).

Liu, Fraser, Koos: "Grueneberg ganglion olfactory subsystem employs a cGMP signaling pathway." in: The Journal of comparative neurology, Vol. 516, Issue 1, pp. 36-48, (2009) (PubMed).

Thompson, Chand, Jonas, Burrin, Steinhelper, Wheeler-Jones, McArdle, Fowkes: "Molecular characterisation and functional interrogation of a local natriuretic peptide system in rodent pituitaries, alphaT3-1 and LbetaT2 gonadotroph cells." in: The Journal of endocrinology, Vol. 203, Issue 2, pp. 215-29, (2009) (PubMed).

Zhu, Strada, Stevens: "Cyclic GMP-specific phosphodiesterase 5 regulates growth and apoptosis in pulmonary endothelial cells." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 289, Issue 2, pp. L196-206, (2005) (PubMed).

Target Details

Target: Natriuretic Peptide Receptor B / PGCB

UniProt: P20594