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PDE8A antibody (N-Term)

There are 3+ publications for this product available. The Rabbit Polyclonal anti-PDE8A antibody is suitable to detect PDE8A in samples from Human, Mouse, Rat and Monkey. It has been validated for WB, ELISA, IHC, IP, IF, ICC and CM.
Catalog No. ABIN2747208
$495.38
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 1 to 3 Business Days

Quick Overview for PDE8A antibody (N-Term) (ABIN2747208)

Target

See all PDE8A Antibodies
PDE8A (phosphodiesterase 8A (PDE8A))

Reactivity

  • 42
  • 10
  • 9
  • 7
  • 5
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Human, Mouse, Rat, Monkey

Host

  • 38
  • 4
Rabbit

Clonality

  • 39
  • 3
Polyclonal

Conjugate

  • 25
  • 5
  • 5
  • 3
  • 2
  • 2
This PDE8A antibody is un-conjugated

Application

  • 28
  • 25
  • 22
  • 7
  • 7
  • 6
  • 5
  • 4
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Confocal Microscopy (CM)
  • Binding Specificity

    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Purification

    Affinity Purified

    Immunogen

    Synthetic peptide common to all PDE8A variants.

    Isotype

    IgG
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.65 μg/μL
  • Maréchal, Guillemette, Goupil, Blondin, Leclerc, Richard: "Cyclic nucleotide phosphodiesterases in human spermatozoa and seminal fluid: Presence of an active PDE10A in human spermatozoa." in: Biochimica et biophysica acta, Vol. 1861, Issue 2, pp. 147-156, (2017) (PubMed).

    Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

    Vang, Housley, Dong, Basole, Ben-Sasson, Kream, Epstein, Clark, Brocke: "Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac." in: The Biochemical journal, Vol. 456, Issue 3, pp. 463-73, (2013) (PubMed).

  • Target

    PDE8A (phosphodiesterase 8A (PDE8A))

    Alternative Name

    PDE8A

    NCBI Accession

    NM_008803

    UniProt

    Q86XV4

    Pathways

    cAMP Metabolic Process
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