PDE8A antibody (N-Term)

Catalog No. ABIN2747208

The Rabbit Polyclonal anti-PDE8A antibody has been validated for WB, ELISA, IHC, IP, IF, ICC and CM. It is suitable to detect PDE8A in samples from Human, Mouse, Rat and Monkey. There are 3+ publications available.

Quick Overview for PDE8A antibody (N-Term) (ABIN2747208)

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE8A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Confocal Microscopy (CM)

Product Details anti-PDE8A Antibody

Binding Specificity: N-Term

Purification: Affinity Purified

Immunogen: Synthetic peptide common to all PDE8A variants.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.65 μg/μL

References for anti-PDE8A antibody (ABIN2747208)

Maréchal, Guillemette, Goupil, Blondin, Leclerc, Richard: "Cyclic nucleotide phosphodiesterases in human spermatozoa and seminal fluid: Presence of an active PDE10A in human spermatozoa." in: Biochimica et biophysica acta, Vol. 1861, Issue 2, pp. 147-156, (2017) (PubMed).

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Vang, Housley, Dong, Basole, Ben-Sasson, Kream, Epstein, Clark, Brocke: "Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac." in: The Biochemical journal, Vol. 456, Issue 3, pp. 463-73, (2013) (PubMed).

Target Details for PDE8A

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Alternative Name: PDE8A

NCBI Accession: NM_008803

UniProt: Q86XV4

Pathways: cAMP Metabolic Process