PDE8A antibody (C-Term)

Catalog No. ABIN2747210

This Rabbit Polyclonal antibody specifically detects PDE8A in WB, ELISA, IHC, IP, IF, ICC and CM. It exhibits reactivity toward Human, Mouse, Rat and Monkey and has been mentioned in 3+ publications.

Quick Overview for PDE8A antibody (C-Term) (ABIN2747210)

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE8A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Confocal Microscopy (CM)

Product Details anti-PDE8A Antibody

Binding Specificity: C-Term

Purification: Affinity Purified

Immunogen: Synthetic peptide common to all PDE8A variants.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.75 μg/μL

References for anti-PDE8A antibody (ABIN2747210)

Kelly, Adamowicz, Bove, Hartman, Mariga, Pathak, Reinhart, Romegialli, Kleiman: "Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain." in: Cellular signalling, Vol. 26, Issue 2, pp. 383-97, (2014) (PubMed).

Kruse, Møller, Kruuse: "Distribution of PDE8A in the nervous system of the Sprague-Dawley rat." in: Journal of chemical neuroanatomy, Vol. 42, Issue 3, pp. 184-91, (2012) (PubMed).

Bol, Booiman, Bunnik, Moerland, van Dort, Strauss, Sieberer, Schuitemaker, Kootstra, van t Wout: "Polymorphism in HIV-1 dependency factor PDE8A affects mRNA level and HIV-1 replication in primary macrophages." in: Virology, Vol. 420, Issue 1, pp. 32-42, (2011) (PubMed).

Target Details for PDE8A

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Alternative Name: PDE8A

NCBI Accession: NM_008803

UniProt: Q86XV4

Pathways: cAMP Metabolic Process