AGPS antibody (AA 158-384)

Catalog No. ABIN2749041

The Mouse Monoclonal anti-AGPS antibody is suitable to detect AGPS in samples from Human. It has been validated for WB and ICFC.

Quick Overview for AGPS antibody (AA 158-384) (ABIN2749041)

Target: AGPS (Alkylglycerone Phosphate Synthase (AGPS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AGPS antibody is un-conjugated

Application: Western Blotting (WB), Intracellular Flow Cytometry (ICFC)

Clone: AGPS-03

Product Details anti-AGPS Antibody

Binding Specificity: AA 158-384

Purpose: Anti-AGPS Purified

Cross-Reactivity (Details): Human

Characteristics: The mouse monoclonal antibody AGPS-03 recognizes AGPS (alkykglycerone phosphate synthase), an intracellular peroxisomal enzyme important for lipid biosynthesis.

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: recombinant human AGPS (amino acids 158-384)

Isotype: IgG2a

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
Western blotting: Recommended dilution: 1-2 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for AGPS

Target: AGPS (Alkylglycerone Phosphate Synthase (AGPS))

Alternative Name: AGPS

Background: Alkylglycerone phosphate synthase,AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.,ADAS, ADPS, RCDP3, ADAP-S, ADHAPS, ALDHPSY

Gene ID: 8540

UniProt: O00116

Pathways: SARS-CoV-2 Protein Interactome