AGPS antibody (AA 158-384) (APC)

Catalog No. ABIN7505837

The APC-conjugated Mouse Monoclonal anti-AGPS antibody (Clone AGPS-03) (ABIN7505837) specifically detects AGPS in ICFC. The antibody is reactive with Human samples.

Quick Overview for AGPS antibody (AA 158-384) (APC) (ABIN7505837)

Target: AGPS (Alkylglycerone Phosphate Synthase (AGPS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AGPS antibody is conjugated to APC

Application: Intracellular Flow Cytometry (ICFC)

Clone: AGPS-03

Product Details anti-AGPS Antibody (APC)

Binding Specificity: AA 158-384

Purpose: Anti-AGPS APC

Characteristics: The mouse monoclonal antibody AGPS-03 recognizes AGPS (alkykglycerone phosphate synthase), an intracellular peroxisomal enzyme important for lipid biosynthesis.

Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: recombinant human AGPS (amino acids 158-384)

Isotype: IgG2a

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular staining.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze,Protect from prolonged exposure to light

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for AGPS

Target: AGPS (Alkylglycerone Phosphate Synthase (AGPS))

Alternative Name: AGPS

Background: Alkylglycerone phosphate synthase,AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.,ADAS, ADPS, RCDP3, ADAP-S, ADHAPS, ALDHPSY

Gene ID: 8540

UniProt: O00116

Pathways: SARS-CoV-2 Protein Interactome