PDE4D5 antibody

Catalog No. ABIN2750963

Cited in 3+ publications. The Rabbit Polyclonal anti-PDE4D5 antibody (ABIN2750963) specifically detects PDE4D5 in CM, ICC, IF, IP, IHC, ELISA and WB. The antibody is reactive with Mouse and Rat samples.

Quick Overview for PDE4D5 antibody (ABIN2750963)

Target: PDE4D5

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Confocal Microscopy (CM), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Product Details

Purification: Affinity Purified

Immunogen: Synthetic peptide corresponding to unique amino acid sequence on :DE4D5 variant gene.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.65 μg/μL

References

Mahavadi, Nalli, Kumar, Hu, Kuemmerle, Grider, Murthy: "Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle." in: American journal of physiology. Cell physiology, Vol. 307, Issue 4, pp. C402-11, (2014) (PubMed).

Li, Cheng, Huang, Conti, Wilson, ODonnell, Zhang: "Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 1, pp. 172-83, (2011) (PubMed).

Murthy, Sriwai: "Stimulatory phosphorylation of cAMP-specific PDE4D5 by contractile agonists is mediated by PKC-dependent inactivation of protein phosphatase 2A." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 294, Issue 1, pp. G327-35, (2008) (PubMed).

Target Details

Target: PDE4D5

UniProt: Q08499