PDE5A antibody (phosphorylated)

Catalog No. ABIN2750986

The Rabbit Polyclonal anti-PDE5A antibody has been validated for WB, ELISA, IHC, IP and ICC. It is suitable to detect PDE5A in samples from Human, Rat, Mouse, Cow and Pig. There are 4+ publications available.

Quick Overview for PDE5A antibody (phosphorylated) (ABIN2750986)

Target: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Reactivity: Human, Rat, Mouse, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE5A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-PDE5A Antibody

Binding Specificity: AA 120-170, phosphorylated

Purification: Affinity Purified

Immunogen: Phosphorylated synthetic peptide common to all PDE5A variants taken within amino acid region 120-170 on human PDE5A protein.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0-1.25 μg/μL

References for anti-PDE5A antibody (ABIN2750986)

Rajagopal, Nalli, Kumar, Bhattacharya, Hu, Mahavadi, Grider, Murthy: "Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation." in: The Journal of pharmacology and experimental therapeutics, Vol. 352, Issue 3, pp. 509-18, (2015) (PubMed).

Bautista Niño, Durik, Danser, de Vries, Musterd-Bhaggoe, Meima, Kavousi, Ghanbari, Hoeijmakers, ODonnell, Franceschini, Janssen, De Mey, Liu, Shanahan, Franco, Dehghan, Roks: "Phosphodiesterase 1 regulation is a key mechanism in vascular aging." in: Clinical science (London, England : 1979), Vol. 129, Issue 12, pp. 1061-75, (2015) (PubMed).

Luong, Rey-Perra, Vadivel, Gilmour, Sauve, Koonen, Walker, Todd, Gressens, Kassiri, Nadeem, Morgan, Eaton, Dyck, Archer, Thébaud: "Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia." in: Circulation, Vol. 123, Issue 19, pp. 2120-31, (2011) (PubMed).

Monfort, Muñoz, Felipo: "Chronic hyperammonemia in vivo impairs long-term potentiation in hippocampus by altering activation of cyclic GMP-dependent-protein kinase and of phosphodiesterase 5." in: Journal of neurochemistry, Vol. 94, Issue 4, pp. 934-42, (2005) (PubMed).

Target Details for PDE5A

Target: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Alternative Name: PDE5A

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling