CD200R1 antibody (N-Term)

Catalog No. ABIN2764056

The Rabbit Polyclonal anti-CD200R1 antibody (ABIN2764056) specifically detects CD200R1 in ELISA. The antibody is reactive with Human samples.

Quick Overview for CD200R1 antibody (N-Term) (ABIN2764056)

Target: CD200R1 (CD200 Receptor 1 (CD200R1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD200R1 antibody is un-conjugated

Application: ELISA

Product Details anti-CD200R1 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human

Characteristics: Ox2r, Hypocretin receptor type 2,As first published in 1998 by Sakurai et al, the initial neuropeptides Orexin A and Orexin B were shown to be important in the regulation of appetite. Continued research now suggests that these peptides also influence a wide range of physiological and behavioral processes such as increased EFG arousal and wakefulness and locomotor activity. In addition to the orexins , two G-protein coupled receptors, designated orexin receptor-1 and orexin receptor-2, have been identified which presumably mediate the signaling events from these neuropeptides1. Recently orexin receptors have been found to activate extracellular signal-regulated kinases in CHO cells, namely ERK phosporylation, through Ca2+ influx..2. Further studies seem to indicate a mechanism for orexin receptor mediated cell death and suggest a pathway from GPCRs to apoptosis throughthe MAPK pathways.3

Purification: Antigen Immunoaffiinity Purification

Immunogen: Synthetic peptide madde to recombinant Human Orexin Receptor Type 2

Isotype: IgG

Application Details

Application Notes: Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Buffer: Affinity purified polyclonal antibody provided as solution in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for CD200R1

Target: CD200R1 (CD200 Receptor 1 (CD200R1))

Alternative Name: Orexin Receptor-2

UniProt: O43614