TRIM45 antibody (N-Term)

Catalog No. ABIN2773822

This Rabbit Polyclonal antibody specifically detects TRIM45 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Pig and Cow.

Quick Overview for TRIM45 antibody (N-Term) (ABIN2773822)

Target: TRIM45 (Tripartite Motif Containing 45 (TRIM45))

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM45 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRIM45 Antibody

Binding Specificity: N-Term

Purpose: TRIM45 Antibody - N-terminal region

Sequence: FKAPRLLPCL HTVCTTCLEQ LEPFSVVDIR GGDSDTSSEG SIFQELKPRS

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TRIM45. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM45

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43330-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM45

Target: TRIM45 (Tripartite Motif Containing 45 (TRIM45))

Alternative Name: TRIM45

Background:

Background Information: TRIM45 is a member of the tripartite motif family. It may function as a transcriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described. TRIM45 belongs to a family of tripartite motif (TRIM) proteins that play important roles in a variety of cellular functions, including cell proliferation, differentiation, development, oncogenesis, and apoptosis (Wang et al., 2004 [PubMed 15351693]).[supplied by OMIM].

Gene Name: Tripartite motif containing 45

Alternative Symbols: RNF99

Protein Name: Tripartite motif-containing protein 45

Molecular Weight: 64kDa

Gene ID: 80263

NCBI Accession: NP_079464

UniProt: Q9H8W5