OS9 antibody (C-Term)

Catalog No. ABIN2773850

This Rabbit Polyclonal antibody specifically detects OS9 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for OS9 antibody (C-Term) (ABIN2773850)

Target: OS9 (Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OS9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OS9 Antibody

Binding Specificity: C-Term

Sequence: LKEIFFNILV PGAEEAQKER QRQKELESNY RRVWGSPGGE GTGDLDEFDF

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against OS9. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human OS9

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for OS9

Target: OS9 (Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9))

Alternative Name: OS9

Background: This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: ERLEC2, OS-9
Protein Interaction Partner: SYVN1, SEL1L, UBC, DCSTAMP, SERPINI1, FBXO6, EGFR, DERL2, CLN5, SNRPD2, SMAD2, FOXM1, ACVR1B, ZNF512B, env, CREB3, RBX1, UBE2J1, CERCAM, NUP210, OS9, HYOU1, VCP, HSP90B1, PPIB, PLOD2, HSPA5, SERPINH1, BSG, FOXRED2, COLGALT1, UGGT2, DNAJB11, ERLEC1, HIF1A,
Protein Size: 667

Molecular Weight: 73 kDa

Gene ID: 10956

NCBI Accession: NM_006812, NP_006803

UniProt: Q13438

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome