Peroxiredoxin 1 antibody (N-Term)

Catalog No. ABIN2773920

The Rabbit Polyclonal anti-Peroxiredoxin 1 antibody has been validated for WB and IHC. It is suitable to detect Peroxiredoxin 1 in samples from Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for Peroxiredoxin 1 antibody (N-Term) (ABIN2773920)

Target: Peroxiredoxin 1 (PRDX1)

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Peroxiredoxin 1 Antibody

Binding Specificity: N-Term

Sequence: SSGNAKIGHP APNFKATAVM PDGQFKDISL SDYKGKYVVF FFYPLDFTFV

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against PRDX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRDX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 199 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Peroxiredoxin 1

Target: Peroxiredoxin 1 (PRDX1)

Alternative Name: PRDX1

Background: PRDX1 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. It may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: MSP23, NKEFA, PAG, PAGA, PAGB, PRX1, TDPX2, PRXI
Protein Interaction Partner: FUS, UBC, MDM2, RPA3, RPA2, RPA1, SUZ12, CACYBP, HECTD1, PRDX2, PRKDC, PPP2R5D, METTL1, PARK2, YWHAQ, VHL, EGFR, CDK2, RAD52, MPG, US3, SH2D1B, LUC7L, HCVgp1, PRDX4, IQCB1, BTRC, UBL4A, VCAM1, SMARCD1, FN1, DAB2, ADH5, ABL1, MYD88, MYC, ITGA4, TIPIN, EIF4
Protein Size: 199

Molecular Weight: 22 kDa

Gene ID: 5052

NCBI Accession: NM_002574, NP_002565

UniProt: Q06830

Pathways: p53 Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events