LIAS antibody (C-Term)

Catalog No. ABIN2773926

This Rabbit Polyclonal antibody specifically detects LIAS in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Zebrafish (Danio rerio), Guinea Pig and Saccharomyces cerevisiae.

Quick Overview for LIAS antibody (C-Term) (ABIN2773926)

Target: LIAS (Lipoic Acid Synthetase (LIAS))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Zebrafish (Danio rerio), Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIAS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LIAS Antibody

Binding Specificity: C-Term

Purpose: LIAS Antibody - C-terminal region

Sequence: EYITPEKFKY WEKVGNELGF HYTASGPLVR SSYKAGEFFL KNLVAKRKTK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against LIAS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human LIAS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104513

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for LIAS

Target: LIAS (Lipoic Acid Synthetase (LIAS))

Alternative Name: LIAS

Background:

Background Information: LIAS belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis.The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

Gene Name: Lipoic acid synthetase

Alternative Symbols: LS, LAS, LIP1, PDHLD, HGCLAS, HUSSY-01

Protein Name: Lipoyl synthase, mitochondrial

Molecular Weight: 39kDa

Gene ID: 11019

NCBI Accession: NP_006850

UniProt: O43766

Pathways: Tube Formation