Endothelin 2 antibody (N-Term)

Catalog No. ABIN2774000

Product Details anti-Endothelin 2 Antibody

Target: Endothelin 2 (EDN2)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endothelin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MVSVPTTWCS VALALLVALH EGKGQAAATL EQPASSSHAQ GTHLRLRRCS

Predicted Reactivity: Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against EDN2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human EDN2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 178 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Endothelin 2

Target: Endothelin 2 (EDN2)

Alternative Name: EDN2 (EDN2 Products)

Background: This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation.
Alias Symbols: ET2, PPET2
Protein Interaction Partner: MME, CMA1, KEL,
Protein Size: 178

Molecular Weight: 20 kDa

Gene ID: 1907

NCBI Accession: NM_001956, NP_001947

UniProt: P20800

Pathways: Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones