BBS5 antibody (Middle Region)

Catalog No. ABIN2774032

The Rabbit Polyclonal anti-BBS5 antibody is suitable to detect BBS5 in samples from Human, Mouse, Rat, Guinea Pig, Horse, Cow and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for BBS5 antibody (Middle Region) (ABIN2774032)

Target: BBS5 (Bardet-Biedl Syndrome 5 (BBS5))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BBS5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BBS5 Antibody

Binding Specificity: Middle Region

Purpose: BBS5 Antibody - middle region

Sequence: VEIDSDGHTD AFVAYFADGN KQQDREPVFS EELGLAIEKL KDGFTLQGLW

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against BBS5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BBS5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52931-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BBS5

Target: BBS5 (Bardet-Biedl Syndrome 5 (BBS5))

Alternative Name: BBS5

Background:

Background Information: BBS5 is a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is required for the formation of cilia.This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is required for the formation of cilia. Alternate transcriptional splice variants have been observed but have not been fully characterized.

Gene Name: Bardet-Biedl syndrome 5

Alternative Symbols: -

Protein Name: Bardet-Biedl syndrome 5 protein

Molecular Weight: 39kDa

Gene ID: 129880

NCBI Accession: NP_689597

UniProt: Q8N3I7

Pathways: Hedgehog Signaling