CRAT antibody (N-Term)

Catalog No. ABIN2774052

This Rabbit Polyclonal antibody specifically detects CRAT in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for CRAT antibody (N-Term) (ABIN2774052)

Target: CRAT (Carnitine O-Acetyltransferase (CRAT))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRAT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CRAT Antibody

Binding Specificity: N-Term

Purpose: CRAT Antibody - N-terminal region

Sequence: MKASSRFKAH QDALPRLPVP PLQQSLDHYL KALQPIVSEE EWAHTKQLVD

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 91%, Horse: 85%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against CRAT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CRAT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096270

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRAT

Target: CRAT (Carnitine O-Acetyltransferase (CRAT))

Alternative Name: CRAT

Background:

Background Information: Carnitine acetyltransferase (CRAT) is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments. Different subcellular localizations of the CRAT mRNAs are thought to result from alternative splicing of the CRAT gene suggested by the divergent sequences in the 5' region of peroxisomal and mitochondrial CRAT cDNAs and the location of an intron where the sequences diverge.

Gene Name: Carnitine O-acetyltransferase

Alternative Symbols: CAT, CAT1, NBIA8

Protein Name: Carnitine O-acetyltransferase

Molecular Weight: 51kDa

Gene ID: 1384

UniProt: P43155

Pathways: Monocarboxylic Acid Catabolic Process