FEM1B antibody (C-Term)

Catalog No. ABIN2774057

The Rabbit Polyclonal anti-FEM1B antibody has been validated for WB. It is suitable to detect FEM1B in samples from Human, Rat, Mouse, Cow, Dog, Horse, Rabbit and Guinea Pig.

Quick Overview for FEM1B antibody (C-Term) (ABIN2774057)

Target: FEM1B (Fem-1 Homolog B (FEM1B))

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FEM1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FEM1B Antibody

Binding Specificity: C-Term

Sequence: DKSTTGVSEI LLKTQMKMSL KCLAARAVRA NDINYQDQIP RTLEEFVGFH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FEM1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FEM1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 627 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FEM1B

Target: FEM1B (Fem-1 Homolog B (FEM1B))

Alternative Name: FEM1B

Background: FEM1B is a component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. It involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. FEM1B also involved in glucose homeostasis in pancreatic islet.
Alias Symbols: DKFZp451E0710, FIAA, F1A-ALPHA
Protein Interaction Partner: GLI1, HIF1AN, NKX3-1, fem-2, Ppm1f, UBC, RBX1, CUL2, TCEB2, TCEB1, Tnfrsf1a, Fem1b, Fas, Casp3, COPS4, RAD9A, CHEK1, DCUN1D1, COPS5, COPS6, CUL5, NEDD8, KIAA0319, GNB2L1, APAF1,
Protein Size: 627

Molecular Weight: 69 kDa

Gene ID: 10116

NCBI Accession: NM_015322, NP_056137

UniProt: Q9UK73