FRK antibody (N-Term)

Catalog No. ABIN406406

The Rabbit Polyclonal anti-FRK antibody has been validated for WB. It is suitable to detect FRK in samples from Human, Mouse, Rat, Pig, Dog, Guinea Pig, Cow and Horse. There is 1 publication available.

Quick Overview for FRK antibody (N-Term) (ABIN406406)

Target: FRK (Fyn-Related Kinase (FRK))

Reactivity: Human, Mouse, Rat, Pig, Dog, Guinea Pig, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FRK Antibody

Binding Specificity: N-Term

Sequence: LCSPQSQRHG HYFVALFDYQ ARTAEDLSFR AGDKLQVLDT LHEGWWFARH

Predicted Reactivity: Cow: 93%, Dog: 92%, Guinea Pig: 93%, Horse: 85%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against FRK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FRK

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 505 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FRK antibody (ABIN406406)

Zhang, Gong, Wang, Wang, Ran: "[Deoxycholate induces apoptosis in cultured normal human esophageal mucosal epithelial cells]." in: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, Vol. 25, Issue 10, pp. 1240-3, (2005) (PubMed).

Target Details for FRK

Target: FRK (Fyn-Related Kinase (FRK))

Alternative Name: FRK

Background: The specific function of FRK is not yet known.The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.
Alias Symbols: GTK, PTK5, RAK
Protein Interaction Partner: SF3B4, BNIP2, CSK, HSP90AA1, FYN, KHDRBS1, PTEN, RB1,
Protein Size: 505

Molecular Weight: 58 kDa

Gene ID: 2444

NCBI Accession: NM_002031, NP_002022

UniProt: P42685