FRK antibody (Middle Region)

Catalog No. ABIN2785801

Cited in 1 publication. The Rabbit Polyclonal anti-FRK antibody (ABIN2785801) specifically detects FRK in WB. The antibody is reactive with Human, Mouse, Rat, Pig, Dog, Guinea Pig, Cow, Horse and Rabbit samples.

Quick Overview for FRK antibody (Middle Region) (ABIN2785801)

Target: FRK (Fyn-Related Kinase (FRK))

Reactivity: Human, Mouse, Rat, Pig, Dog, Guinea Pig, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FRK Antibody

Binding Specificity: Middle Region

Purpose: FRK Antibody - middle region

Sequence: DLSYKTVDQW EIDRNSIQLL KRLGSGQFGE VWEGLWNNTT PVAVKTLKPG

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FRK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FRK

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54618-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-FRK antibody (ABIN2785801)

Zhang, Gong, Wang, Wang, Ran: "[Deoxycholate induces apoptosis in cultured normal human esophageal mucosal epithelial cells]." in: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, Vol. 25, Issue 10, pp. 1240-3, (2005) (PubMed).

Target Details for FRK

Target: FRK (Fyn-Related Kinase (FRK))

Alternative Name: FRK

Background:

Background Information: FRK belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.

Gene Name: Fyn-related kinase

Alternative Symbols: GTK, RAK, PTK5

Protein Name: Tyrosine-protein kinase FRK

Molecular Weight: 58kDa

Gene ID: 2444

NCBI Accession: NP_002022

UniProt: P42685